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Cayenne Inc is a contract venture management
and corporate
development firm serving the pharmaceutical, biotechnology and
life science device industries. We advise public and private clients in the areas of strategic planning, market evaluation, competitive assessment and commercialization assistance. From our headquarters in
Maryland, we have clients with operations
throughout the world.
Cayenne services goes beyond being a trusted advisor. We are a strategic partner to
our partners jointly building out their corporate strategy,
portfolios and enhancing their revenues. They rely on us for candid, insightful assistance in creating value from their science.
Cayenne honors that trust by delivering operational and strategic business services
to established and emerging firms as well as to entrepreneurial
scientists.
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Cayenne advances the commercial success of businesses in the life science industries. We apply proven and cutting-edge business techniques to accelerate commercialization of science-based innovation in pharmaceutical, biotechnology,
life science device and other related industries. And we work in close partnership with our clients, to devise realistic solutions to difficult business problems.
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R.
Richard L. Hamer, Ph.D. –
Principal
Rich has a 20-year background covering all aspects
of pharmaceutical research and pharmaceutical research informatics systems
development. He founded Cayenne after leaving Viaken Systems where he
was the Chief Science Officer and VP of Research & Development providing
guidance, management and sales for their contract research programs. Prior
to Cayenne, he spent much of his career with the Hoechst /Aventis Group
initially working on their U.S. Central Nervous Systems Disorders synthesis
program and an inflammatory syntheses program. He initiated the US computational
chemistry group for Hoechst, and created their U.S.-based automated screening
facility and research informatics group to capture and integrate the screening
data flow with a new chemical informatics system. Rich founded the global
bioinformatics group for Hoechst Marion Roussel, and co-founded a biotechnology
joint venture, Hoechst-ARIAD Genomics Center.
He received his B.S. in chemistry from Northeast
Missouri State University and a Ph.D. in medicinal chemistry from the
University of Iowa. His doctorate research was directed toward the synthesis
of rigid analogs of dopamine as anti-psychotic agents. Rich has produced
28 publications and presentations and is co-inventor on 42 U.S. patents.
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Michael
Provance – Principal
Mike has a background in management of emerging technology companies.
Prior to Cayenne, he ran revenue operations that included consulting and
infrastructure services for Viaken Systems, a life sciences informatics
services and software company. He joined Viaken from U.S. Interactive,
Inc., a strategic consulting firm where he served as the vice president
and general manager for its Washington, D.C. office and grew this office
to $16 million in profitable revenues. Before joining U.S. Interactive,
Mike was the director of advanced technologies and strategic marketing
for a Westinghouse/CBS interactive company. Earlier in his career, Mike
held the positions of general manager for an Internet software company;
and an investment manager at venture capital firm Ben Franklin Technology
Center of Western Pennsylvania.
Mike received his B.S. degree in management
science from Massachusetts Institute of Technology and his M.B.A. from
Penn State’s Smeal College of Business Administration. Mike also served
on the board of the Washington, D.C. Technology Council from 2000-2002.
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In
addition to the Principals' skills, Cayenne's staff has also
been engaged in a number of collaborative development
projects. Our scientists and information technologists take
a collaborative approach in developing solutions to each new
data generative and research process that meet the business
and research goals of our clients.
STATISTICAL
ANALYSIS, DATA MINING AND ALGORITHM DEVELOPMENT
- Developed
disease and toxicity models via statistical methods
for analysis of microarray data
- Created
protocols for the ranking of therapeutic targets based
upon derived and extracted data
- Developed
database, algorithms and interfaces for processing and
analysis of Medline Citation references
IN-SILICO
TECHNIQUES FOR TARGET SELECTION THROUGH APPLICATION OF
DATA AND TEXTUAL ANALYSIS
- Developed
methods for extraction of potential target
therapeutics through automated analysis of text based
information linked to structured data derived and
captured from laboratory experiments
SOFTWARE
AND COMPUTE ENVIRONMENT DEVELOPMENT AND ALGORITHM DESIGN
- Developed
methods to discover single nucleotide polymorphisms (SNPs)
and co-designed laboratory techniques and software for
a high-throughput SNP discovery
- Developed
grid computing environment and rewrote existing
scientific algorithms to work efficiently in the grid
environment
- Refined
and developed optimal code to use large compute
clusters as well as smaller Intel compute clusters
PROCESS
ENGINEERING (RESEARCH, PROCUREMENT, QC, PRODUCT DESIGN,
MANUFACTURING AND CUSTOMER SUPPORT) AND DATABASE DESIGN
- Engaged
by a manufacturing group to analyze and improve their
design and manufacture of high-density DNA microarrays.
The output consisted of hardware and bioinformatics
software, high performance computing and in
large-scale database design.
DATABASE
MODELING, DESIGN AND INTERFACE DEVELOPMENT
- Developed
a unified derivative database with appropriate
analysis tools for mouse sequence and library
information
- Designed
and implemented a data warehouse and supporting data
collection and analysis tools for a NIDA clinical
informatics management system. This system matched the
specifications for multiple protocols, multi-year
programs and large number of clinical trial sites.
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